How to Use Biochemistry Analyzer

The chemistry analyzer is one of the most important analytical instruments frequently used in clinical testing. It measures various biochemical indicators by analyzing blood or other bodily fluids. Whether you are an experienced laboratory technician or a novice, understanding how to use a biochemical analyzer to obtain reliable results is crucial. But how exactly does a chemistry analyzer work? What steps should be followed to ensure optimal performance? In this comprehensive guide, we will walk you through the process of using a biochemical analyzer.

What is biochemistry analyzer

A chemistry analyzer is an instrument that uses photometric colorimetry to measure specific chemical components in body fluids. It is a type of blood biochemistry analysis equipment. By detecting the levels of various chemical substances in the blood, it assists doctors in assessing kidney function, liver function, blood sugar, blood lipids, electrolytes, and coagulation status, providing important evidence for clinical diagnosis and treatment.

A biochemical analyzer is a device used to measure the concentration of specific substances in biological samples such as blood or urine. These measurement results play a crucial role in disease diagnosis, health monitoring, and the formulation of treatment plans.

Generally, biochemical analyzers are divided into two categories:

Semi-automatic analyzers

Certain steps require manual intervention, offering flexibility and cost-effectiveness.

Semi-auto Biochemistry Analyzer

Test Method : 1 point end, 2 point end (Sample blank), Kinetics, Fixed-time, Coagulation

Flow Cell : 32ul, 10mm

Wavelength : 7 standard filters: 340, 405, 450, 505, 546, 578, 630 nm. 2 more for optional.

Economical Semi-auto Biochemistry Analyzer

Test Method : 1 point end, 2 point end(Sample blank), Kinetics, Fixed-time

Flow Cell : 32ul, 10mm

Wavelength : 7 standard filters: 340, 405, 450, 505, 546, 578, 630. 2 more for optional.

Semi-auto Biochemistry Analyzer

Test Mode : Kinetic, End point, Two point, Absorbance

Flow Cell : 32 μL quartz glass, 10 mm

Wavelength : 7 standard filters, 340, 405, 492, 510, 546, 578, 630 nm, 1 free position

Fully automated analyzers

Automate all steps in the analysis process, including sample collection, reagent addition, mixing, temperature-controlled reactions, detection, result calculation and display, and cleaning. They can fully replicate and replace manual operations, making them ideal for high-throughput laboratories.

Best Fully Automatic Biochemistry Analyzer

Test Speed : Constant 200

tests/hour; Constant 200 tests/hour

Test Principle Colorimetric method, turbidimetry

Test Method 1 point end, 2 point end, Fixed-Time, Kinetics

How the Chemistry Analyzer works

The working principle of the chemistry analyzer is based on photometric colorimetry. First, samples such as blood or urine are reacted with specific reagents to produce colored compounds. The instrument then illuminates the reacted samples with light of a specific wavelength and measures the degree of light absorption. According to the Beer-Lambert law, absorbance is directly proportional to the concentration of the substance. The photodetector converts the absorbed light signal into an electrical signal, which the system uses to calculate the concentration of specific chemical components in the sample. The results are then displayed on the screen for clinical diagnosis and analysis.

A monochromator decomposes the complex colored light emitted by the light source into monochromatic light.

Monochromatic light of a specific wavelength passes through a cuvette containing the sample solution.  

A photoconverter converts the incident light into an electrical signal, which is sent to the signal processing system for analysis.  

The computer then processes, calculates, analyzes, and saves the measurement data according to the user-selected operating mode.  

The printer simultaneously prints the corresponding results.  

Finally, after each set of samples is measured, the cuvette and tubing are clean.

Operating steps for the Chemistry Analyzer

Sample preparation: Cell impurities are removed by centrifugation, and the sample is diluted or treated with reagents.  

Sample analysis: The sample is injected into a channel containing reagents and enzymes, producing a color or fluorescence change.  

Detection and measurement: The instrument measures the signal intensity, compares it with a calibration curve, and calculates the target concentration.

Data analysis: The instrument generates a report displaying all detection results and reference ranges.

In summary, the working principle of a biochemical analyzer is based on the interaction between biological samples and specific reagents, as well as the detection and measurement of the resulting chemical reactions. This process enables precise measurement of various biochemical parameters in biological fluids, thereby aiding in the diagnosis, monitoring, and treatment of various diseases and conditions.

Conclusion

Proper use of biochemical analyzers not only ensures the accuracy of test results, but also improves laboratory efficiency and diagnostic reliability. Following operating procedures, performing regular maintenance on equipment, and paying attention to quality control are key to achieving efficient and stable operation. Through scientific use, biochemical analyzers can provide strong support for clinical diagnosis.