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Bioreactor, High-precision Control

Model : BIOR-M1P; BIOR-M2P; BIOR-M3P; BIOR-M5P; BIOR-M7P; BIOR-M10P; BIOR-M15P

Total Volume (L): 1/2/3/5/7/10/15
Flow Meter: 2 rotameters + 1 MFC
Gas Source: Air, O2
Material (Vessel): Boro 3.3 high borosilicate glass
Temperature Range: 0~150.0 °C
PH Range: 2.00~12.00
DO Range: 0.0~150.0%
The high-precision control bioreactor is equipped with 1 MFC, featuring higher control accuracy and greater stability.
Availability:
Quantity:

High-precision Control Bioreactor Advantage:

1. Enhanced Efficiency & Professionalism: Automated gas flow control and finely adjustable pump speeds ensure optimal precision.

2. Cost-effective Excellence: Advanced solution for microbial cultivation.

3. User-centric Interface: Large 15.6-inch touchscreen with intuitive graphical design for effortless operation.

4. Quick and Easy Installation: Small footprint and no tools are required for installation.

5. Mature Vessel Manufacturing Process: All components are located on the vessel lid, easy to disassemble, maintain and clean.

6. Reliable Performance and Precise Control: Leading international brands core hardware ensures stability.

7. Versatile Total Volumes: 7 vessel sizes (1 L to 15 L) to suit diverse experimental needs.

8. Powerful Software Functions: Full control via feedback, time, conditions, scripts, etc.

9. Easy Sterilization: The separation of the base, vessel body and stirring motor enables a lightweight design, making it easier for experimenters to transfer it to the sterilizer.

10. Remote Communication: Wired and wireless LAN for remote monitoring and control.

11. Ready to Use after Installation: The complete kit includes everything needed for the application, pre-configured, and ready to use, without the need to purchase additional accessories.

12. Expandable Design: Flexible vessel interchangeability and 1 universal interface for future upgrades.


High-precision Control Bioreactor Specifications: 


Model

BIOR-M1P

BIOR-M2P

BIOR-M3P

BIOR-M5P

BIOR-M7P

BIOR-M10P

BIOR-M15P










Independent Control Tower

Housing Material

Carbon steel, plastic powder coating

Display

15.6" color touch screen

Controller

Siemens S series PLC, MCGS HMI

Integrated Pump

4 Matson Marlow 114 variable-speed peristaltic pumps

Flow Meter

2 rotameters + 1 MFC

Communication

USB [software upgrade, data copy and export], Industrial Ethernet, WiFi, 1 × Analog Input 4 to 20 mA

Interface

1 × pH sensor cable;          1 × DO sensor cable;       2 × stirring motor control wires;            1 × temperature sensor interface;           1 × foam sensor cable;      

1 × heating blanket control wire interface;   1 × main power interface

Water Interface

6 × hose barb fitting (inlet/outlet for exhaust condenser, cooling finger, chilled water)

Air Interface

3 × hose barb fitting (2 × gas supply interface, 1 × gas outlet)

Power Supply

220 V (±10%), 50 Hz, single phase

Rated Power

Max. 1.5 kW                                                                

External Size  (W×D×H)

435×360×730 mm

Net Weight

Approx. 40 kg (depending on configuration)


Agitation Control

Motor

Maintenance-free, low noise servo motor

Speed Range

5 - 1000 rpm

Speed Accuracy

± 0.5%

Rated Power

Max. 750 W



Gas Control

Gas Source

Air, O2

Control Method

1 × MFC, 2 × rotameters, 1 × solenoid valve

Gas Inlet

Ring sparger

Flow Range

Sparger Air: rotameter 3 - 30 L/min, MFC max. 20 SLPM Sparger O2: rotameter 0.5-8 L/min

Flow Accuracy

Rotameter accuracy: ± 4%, MFC accuracy: ± 1%




Temperature Control

Control Method

Robust PID algorithm

Heating Method

Heating blanket

Heating Power

Max. 500 W, each vessel

Cooling Method

Tap water or circulating cooling

Sensor

Pt100 RTD (JUMO, German)

Measurement Range

0~150.0 °C

Measurement Accuracy

± 0.1 °C

Control Range

8.0 °C above coolant to 40.0 °C above ambient (0 - 65.0 °C absolute)

Control Accuracy

± 0.2 °C

PH Control


Control Method

· Robust PID algorithm  · Cascade control with peristaltic pumps by adding acid and alkali

Sensor

Hamilton Sterilizable Gel-filled pH electrode

Measurement Range

2.00~12.00

Measurement Accuracy

0.01

Control Accuracy

± 0.05

DO Control

Control Method

· Robust PID algorithm  · Cascade control with different parameters (agitation, gas flow and pump)

Sensor

Hamilton Sterilizable polarographic DO electrode

Measurement Range

0.0~150.0%

Measurement Accuracy

0.1%

Control Accuracy

± 3%

Foam Control

Control Method  

· Cascade control with peristaltic pump by adding antifoam (defoamer)      · Mechanical defoaming blade


High-precision Control Bioreactor Specification (Glass Vessel) : 

Model
BIOR-M1PBIOR-M2PBIOR-M3PBIOR-M5PBIOR-M7PBIOR-M10PBIOR-M15P
Glass VesselTypeSingle-wall round-bottom cylindrical vessel, available for electric blanket
Total Volume1 L2 L3 L5 L7 L10 L15 L
Max. Working Volume0.75 L1.5 L2.25 L3.75 L5.25 L7.5 L11.25 L
Min. Working Volume0.25 L0.5 L0.75 L1.25 L1.75 L2.5 L3.75 L
Material (Wetted Part)· Glass vessel material: Boro 3.3 high borosilicate glass
· Vessel cover and inner parts: SUS 316 L
· Seal: EPDM and Silicon
Surface Treatment· Inner surface: electrolytic polishing, Ra <0.4 μm
· Outer surface: Ra <0.6 μm
Pressure DesignWorking pressure: 0~1 bar @ 150°C Autoclavable
Height to Diameter Ratio [H: D]Approx. 2:1
Vessel  DimensionsRefer to "Table A"
Vessel Weight (Excluding Motor)8 kg9 kg10 kg12 kg13.5 kg15 kg18 kg
Vessel Lid Interface1 × Agitator flange for top mechanical stirring; 1 × Flame inoculation port;
2 × Baffle port, including cooling coil; 1 × Gas inlet port for ring sparger;
1 × Exhaust port, including water-cooled exhaust condenser; 1 × PH sensor port;
1 × DO sensor port; 1 × PT100 temperature sensor port; 1 × Foam sensor port;
1 × Sampling port N × Feeding port;
Impellers· < 5 L: 2 layers, top: foam breaker, bottom: 6-blade Rushton impeller
· ≥ 5 L: 3 layers, top: foam breaker; middle: 4-blade pitched impeller; bottom: 6-blade Rushton impeller
· Detachable, height adjustable
Baffles· <3 L: 2 removable baffles · ≥ 3 L: 4 removable baffles



Table A: 

Dimension

Vessel Volume

1 L

2 L

3 L

5 L

7 L

10 L

15 L

a (mm)

450

471

567

622

712

753

851

b (mm)

430

450

492

546

636

641

738

c (mm)

227

214

292

347

437

442

484

d (mm)

170

190

230

280

370

360

450

e (mm)

Ø90

Ø110

Ø130

Ø150

Ø160

Ø185

Ø203

f (mm)

180

190

190

212

212

248

270

Sterilization Requirement

Minimum Size (mm)

Ø220×450

Ø230×470

Ø230×500

Ø265×550

Ø265×640

Ø300×645

Ø335×740

Recommended Size (mm)

Ø280×500

Ø280×500

Ø280×555

Ø300×600

Ø300×700

Ø350×700

Ø380×800


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